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Living guidelines updates

The Stroke Foundation’s Clinical Guidelines for Stroke Management are evolving into the world's first living guidelines as the next generation of health evidence translation.

This three-year pilot project is building and evaluating a dynamically updating summary of stroke evidence to guide clinical practice and policy development.

Draft recommendations will be posted here during public consultation.

On this page:
New and updated recommendations
How living guidelines work
Suggest new topics or questions

New and updated recommendations

Recommendations for the following topics have been updated based on new research evidence, in accordance with the 2011 NHMRC Standard for clinical practice guidelines.

Topic Date Change
Thrombolysis 7/11/2019 Time window for thrombolysis extended to 9 hours (including 9 hours from the mid-point of sleep for wake-up stroke) using CT or MR perfusion imaging selection; and thrombolysis with tenecteplase as an alternative to alteplase.
Acute antithrombotic therapy 7/11/2019 Upgrade to strong recommendation for using aspirin plus clopidogrel in minor stroke or high-risk TIA.
Patent foramen ovale (PFO) management 7/11/2019 Percutaneous PFO closure recommended in ischaemic stroke patients aged <60 when the PFO is considered the likely cause of stroke after other aetiologies have been thoroughly excluded.

See all current recommendations in the Clinical Guidelines for Stroke Management.

How living guidelines work

The living guidelines use ‘evidence surveillance’ systems that continually scan for relevant new research, incorporate it into evidence summaries and rapidly update guideline recommendations whenever there is a substantial change in the evidence.

The ultimate goal is to create a near real-time, closed-loop evidence system in which global evidence and local data are integrated for insight and health decision making.

This work will be supported by new evidence systems from Cochrane Australia, including artificial intelligence, the Cochrane Crowd citizen science community, and the Covidence online systematic review platform.

Guideline recommendations will continue to be developed and published using the MAGICapp platform.

Diagram of how the evidence summaries turn newly published research and clinical practice data into updated recommendations, which then feed into clinical practice and policy

Suggest a new topic or question

To keep our living guidelines relevant, we annually review the topics the guidelines cover and the questions about practice that they answer. The current topics make up the table of contents of the Clinical Guidelines.

We welcome your suggestions for new topics that you believe are critical to include. New topics will be considered during our project steering committee's annual review.

Please email your suggestions to guidelines@strokefoundation.org.au


For more information, please contact guidelines@strokefoundation.org.au

This project is a partnership between the Stroke Foundation and Cochrane Australia, and is supported by the Australian government’s Medical Research Future Fund.

Cochrane Australia